Coronavirus vaccine update: 20 mn Americans may get vaccine by December-end

vaccine update: Almost a year after the highly contagious hit the world, hopes of getting an effective vaccine soon have been raised with Pfizer, Moderna, Russia’s Sputnik V, India’s ‘Covaxin’ and the Oxford vaccine showing promising results at different stages of trials. The global Covid-19 tally has surged past 52 million and 1.2 million had died so far. The US, which is the worst-hit country, plans to start distribution of vaccines by December. Along with the US, India, France, Russia and Brazil are struggling to curb the spread of the virus. 

1. India coronavirus update: SII and ICMR complete enrolment of phase 3 trials for Oxford vaccine Covishield

Serum Institute of India (SII) and ICMR on Thursday announced the completion of enrolment process of 1,600 participants in the phase-III clinical trials for COVID-19 vaccine Covishield in the country.

Volunteers on the vaccine trial have compared the jab’s side effects to a ‘severe hangover’ and said it left them with headaches, fever and muscle aches similar to the flu vaccine, the Daily Mail reported.

One 45-year-old volunteer said the first dose left her suffering side effects similar to the flu jab but that her symptoms were ‘more severe’ after her second jab.

Another volunteer, 44-year-old Glenn Deshields, said Pfizer’s vaccine made him feel like he had a ‘severe hangover’ but that symptoms quickly cleared up.

3. Russia progress: Sputnik V vaccine 92 per cent ‘effective’

The Russian ‘Sputnik V’ vaccine for Covid-19 has arrived in India following the nod to Pharma major Dr Reddy’s Laboratories to conduct an adaptive phase 2/3 human clinical trial for the vaccine in the country.

In a video that surfaced on media, containers with logos of Dr Reddy’s and Sputnik V being unloaded from a small truck was seen.

4. 20 million Americans could be corona vaccine by December

Roughly 20 million people could be vaccinated against the coronavirus in December, the chief of the Donald Trump administration’s vaccine coordination program said today. Anywhere from 25 to 30 million people could be vaccinated each month afterward. The speed depends on a big ‘if’ – the US Food and Drug Administration’s emergency use authorization for one or more vaccines.

5. Brazil says Chinese vaccine trial can resume

Brazil health regulator Anvisa on Wednesday allowed the resumption of late-stage clinical trials for China’s Sinovac Covid-19 vaccine, which had been suspended due to the death of a study subject registered in Sao Paulo by suicide.

6. Moderna update

Moderna Inc said on Wednesday it was on track to report early data from a late-stage trial of its experimental later this month, two days after successful interim data from rival Inc’s vaccine. A high degree of effectiveness for the vaccine would make sense as it was “almost identical” to the Pfizer shot, Anthony Fauci, director of the US National Institute of Allergy and Infectious Diseases, said at a conference organised by the Financial Times.

“It may not be 95 per cent, it might be 90 per cent, or 96 per cent, or 89 per cent, but it is going to be up there,” he said.

7. India coronavirus vaccine update

The trial of Bharat Biotech-developed coronavirus vaccine candidate ‘Covaxin’ entered the third phase at Aligarh Muslim University (AMU) on Tuesday and Vice-Chancellor Professor Tariq Mansoor got himself registered to be the first volunteer for the same.

Covaxin Phase-III trial was aimed at evaluating the safety and efficacy of the coronavirus vaccine study led in collaboration with the Indian Council of Medical Research (ICMR) and Bharat Biotech, a release from AMU stated.

8. Coronavirus vaccine cost: BioNTech to price vaccine below market rates

BioNTech, the first in the race to disclose interim data from a large-scale trial showing a highly effective Covid-19 vaccine, is planning to price the two-shot regimen below “typical market rates” and would differentiate pricing between countries and regions.

9. China coronavirus vaccine update

China National Pharmaceutical Group (Sinopharm) said on Wednesday that the data from large-scale, late-stage clinical trials for its unit’s Covid-19 vaccine were “better than expected”. Sinopharm’s unit China National Biotec Group (CNBG) has moved two vaccine candidates into Phase-III clinical trials outside China in multiple countries, including the United Arab Emirates, Bahrain and Egypt involving more 50,000 participants in total.

The trials were nearing their end, Sinopharm said in a statement on Chinese social media WeChat.

10. Canada coronavirus vaccine progress

Canadian drug developer Medicago said a combination of its experimental Covid-19 vaccine and GlaxoSmithKline’s vaccine booster produced virus-neutralising antibodies in all healthy volunteers in an early-stage study. The company, which is backed by Mitsubishi Tanabe Pharma and tobacco giant Philip Morris, said it planned to move into mid-to-late-stage trials with a lower dose version of its vaccine, along with the GSK adjuvant.

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